It appears that until bone graft has not achieved 100% success, intraradicular diseases remain controversial and therefore, different treatment plans are suggested for them. Treating intraradicular diseases depend on many factors: maxillary molars are more prone to bone loss and have worse prognosis. To assess prognosis more carefully these factors should be considered: 1) bone loss: its apical depth, local or generalized 2) bone condition: buccal, lingual, mesial and distal aspects 3) tooth mobility: grades 2 and 3 have not good prognosis. Crown root ratio is also important. 4) the angle of divergence of roots: the more the roots are divergent, the better the prognosis would be. 5)adjacent teeth health 6)tooth position in jaws 7) age and general health of the patients 8) oral hygiene In general, teeth with 2 roots can be treated more effectively than 3 root ones. Maxillary first premolars are exceptions that do not respond to the treatments positively. We should look forward to the future investigations and findings.
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