Volume 15, Issue 4 (9 2002)                   jdm 2002, 15(4): 68-87 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Lotfazar M. Papillon Lefevre Syndrome. jdm. 2002; 15 (4) :68-87
URL: http://jdm.tums.ac.ir/article-1-440-en.html
Abstract:   (7132 Views)
Papillon Lefevre Syndrome (PLS) is a rare recessive autosomal disease, which is associated with palm and sole hyperkeratosis and early periodontium break down of deciduouse and permanent dentition. In the differential diagnosis of PLS, congenital form of palm and sole hyperkeratosis should be considered.Recently, mutation in catepesin C gene has been recognized as a genetic basis for PLS disease. In this disease, complete lack of catepesin C enzyme activity, due to the mutations on both allels, are observed. Actinobacillous actinomycetemcomitans (A.a) bacteria are presented as the main periodontal pathogene in PLS disease. The treatment results have been contradictory and no agreement has been obtained in this regard. Elimination of A.a bacteria and administration of synthetic retinoids are reported as a suitable treatment.
Full-Text [PDF 1675 kb]   (3336 Downloads)    
Type of Study: Research | Subject: general
Published: 2013/09/17

Add your comments about this article : Your username or Email:
CAPTCHA

© 2020 All Rights Reserved | Journal of Dental Medicine

Designed & Developed by : Yektaweb