Volume 27, Issue 4 (1-2015)                   jdm 2015, 27(4): 254-258 | Back to browse issues page

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Roza H, Mohammad Bagher R, Hamid Reaza H, Nazila A, Mehdi Salehi Z. Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitro. jdm. 2015; 27 (4) :254-258
URL: http://jdm.tums.ac.ir/article-1-5261-en.html
Abstract:   (5473 Views)

  Background and Aims: Dental caries is one of the most common infectious diseases which could be prevented in various ways. The aim of the present study was to evaluate the effect of a toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient caries.

  Materials and Methods: 9 sound first premolar teeth of maxilla and mandible were sectioned to four pieces. 6 specimens were stored in distilled water as control group. The remaining 30 specimens were demineralized for 72 hours and then their microhardness was measured. 0, 0.5, 1, 2 and 5% wt nano-hydroxyapatite were added to the solution of distilled water and toothpaste. Specimens were divided into 5 groups (N=6) and after demineralization, each group were randomly immersed in the above-mentioned solutions for 15 minutes. Next, specimens were kept in artificial saliva for 1 hour followed by immersion in the related remineralizing solution for another 15 minutes. This procedure was repeated for 5 days. Finally, the microhardness of the teeth was measured. Data were analyzed using repeated measures analysis of variance (ANOVA).

  Results: The microhardness of demineralized teeth was increased following exposure to different concentrations of nano-hydroxyapatite, but this increase was not statistically significant (P=0.62).

  Conclusion: Nano-hydroxy apatite can enhance remineralization and increase the tooth microhardness although this increase was not significant.

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Type of Study: Research | Subject: general
Received: 2014/12/22 | Accepted: 2014/12/22 | Published: 2014/12/22

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