Volume 30, Number 1 (6-2017)                   jdm 2017, 30(1): 12-17 | Back to browse issues page


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Khoroushi M, Khorasgani M R, Aliasghari A. Determination of minimum inhibitory concentration (MIC) of two plants extract on cariogenic streptococci. jdm. 2017; 30 (1) :12-17
URL: http://jdm.tums.ac.ir/article-1-5609-en.html

1- Professor, Department of Operative Dentistry, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran; Member of Dental Materials Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran Professor, Department of Operative Dentistry, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran; Member of Dental Materials Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
2- Associate Professor, Department of Microbiology, Faculty of Biology, University of Isfahan, Isfahan, Iran Associate Professor, Department of Microbiology, Faculty of Biology, University of Isfahan, Isfahan, Iran
3- Graduate Student, Department of Microbiology, Faculty of Biology, University of Isfahan, Isfahan, Iran Graduate Student, Department of Microbiology, Faculty of Biology, University of Isfahan, Isfahan, Iran
Abstract:   (635 Views)

Background and Aims: Tooth decay has high prevalence in the world. The use of plant material for the prevention and treatment of this disease for various reasons is considered, due to the increasing resistance of bacteria to antibiotics, the high cost and adverse effects of some chemicals used in dentistry. This study was aimed to determine the antimicrobial effect of alcoholic extract of Pepper (Capsicum annuum) and eggplant skin and cap on the cariogenic streptococci.

Materials and Methods: In this study, the antimicrobial activity of ethanol extract of Capsicum annuum and eggplant skin and cap on the cariogenic streptococci, including Streptococcus mutans, Streptococcus sobrinus, and Streptococcus sanguis by microtitre plate method for MIC (Minimum Inhibitor Concentration) was performed. Data were analyzed by one-way analysis of variance using Prism 5 Graph Pad software.

Results: MIC for the Capsicum annuum and eggplant skin for Streptococcus mutans was 250 mg/ml (SD=0.052), and for the Streptococcus sobrinus and Streptococcus sanguis was 125 mg/ml (SD=0.027). The MIC for the cap eggplant for Streptococcus mutans and Streptococcus sobrinus was 500 mg/ml (SD=0) and for S. sanguis was getting 125 mg/ml (SD=0.159).

Conclusion: This study showed that the herbal extracts of Capsicum annuum and eggplant skin and cap had beneficially antimicrobial effects on all three strains of cariogenic streptococci.

Full-Text [PDF 826 kb]   (254 Downloads)    
Type of Study: Research | Subject: general
Received: 2017/06/11 | Accepted: 2017/06/11 | Published: 2017/06/11

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